Abstract advances in pulmonary neuroendocrine tumor management by kjell oberg the spectrum of neuroendocrine tumors nets of the lung include on the one hand typical carcinoids and atypical carcinoids with a more indolent behavior and on the other hand the highly aggressive poorly differentiated large and small cell carcinomas. Neuroendocrine tumors of the lung current challenges and advances in the diagnosis and management of well differentiated disease andrew e hendifar md mpha alberto m marchevsky mdb richard tuli md phdc adepartment of medicine cedars sinai medical center los angeles california. Neuroendocrine tumors nets comprise a heterogeneous group of malignancies that arise from neuroendocrine cells throughout the body and most commonly originate from the lungs small intestine and rectum 1 lung nets originate from pulmonary neuroendocrine cells pnecs that occur as individual cells or small pnec clusters neuroepithelial . Neuroendocrine tumors nets comprise a heterogeneous group of malignancies that arise from neuroendocrine cells throughout the body most commonly originating from the lungs and gastrointestinal tract lung nets can be classified as well differentiated low grade typical carcinoids tcs and intermediate grade atypical carcinoids acs and poorly differentiated high grade large cell . Advances in the diagnosis and management of well differentiated and intermediate differentiated neuroendocrine tumors of the lung it is therefore recommended that each case be assessed in consultation with several experts within a multidisciplinary tumor board specializing in pulmonary wd travispathology and diagnosis of
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